Brian McNaughton is an accomplished educator and scientific professional hailing from Phoenixville, PA, whose expertise spans various domains within biologics drug discovery and large molecule pharmaceutical science. With a fervent dedication to advancing therapeutic discovery and care, McNaughton has carved a distinguished niche for himself in the field.
Specializing in protein evolution, intracellular biologics delivery, nanobody-based immunotherapeutic discovery, and RNA-targeted protein and peptide drug discovery, McNaughton’s breadth of knowledge is matched only by his passion for mentorship and education. He ardently nurtures future generations, imparting invaluable insights to propel the field forward.
A driving force behind McNaughton’s endeavors is his aspiration to shape the next era of therapeutics. His pioneering research has garnered prestigious accolades, including an NIH Research Grant aimed at exploring novel protein/RNA interactions. Currently spearheading four research projects, McNaughton’s commitment to expanding the therapeutic utility and understanding remains unwavering.
In addition to his research pursuits, Brian McNaughton serves as a Senior Fellow and Adjunct Professor, offering courses in Modern Organic Chemistry, Physical Organic Chemistry, Immunology, and Molecular Biology. His illustrious academic journey includes roles as an Associate Professor at Colorado State University and a Postdoctoral Fellow at Harvard University, during which he co-authored twelve research papers.
McNaughton’s academic prowess is underpinned by a robust educational foundation, having earned his Bachelor of Science in Chemistry from Indiana University of Pennsylvania before obtaining his Doctorate in Chemistry (Chemical Biology) from the University of Rochester.
A prolific author, McNaughton has published numerous research papers elucidating complex topics such as RNA recognition motifs and antibody therapeutics, contributing significantly to medical understanding and cancer treatment options.
Beyond his professional pursuits, McNaughton finds solace in outdoor activities like golf and hiking, cherishing quality time with his loved ones. An avid traveler and enthusiast of diverse cuisines, he seeks to instill a sense of wonder in his children through exploration. Additionally, McNaughton channels his creativity into painting, reveling in the boundless expression offered by the vibrant world of colors and canvases.
What is your typical day, and how do you make it productive?
It varies tremendously, Some days I’m working in the lab, while other days I focus on planning research activities, data analysis,
How do you bring ideas to life?
I ensure that I work with teams of talented individuals with a diverse approach and skill set.
What’s one trend that excites you?
I am excited by the potential of gene editing technologies and novel immunotherapeutics designed to target the destruction of diseased cells
What is one habit that helps you be productive?
Keeping up to date with recent literature and research findings, as well as detailed planning.
What advice would you give your younger self?
Be more patient, both in your career and personal life
What is the one thing you repeatedly do and recommend everyone else do?
Take time to reflect on the present.
When you feel overwhelmed or unfocused, what do you do?
I go for a walk.
What is one strategy that has helped you grow your business or advance in your career?
Perseverance and learning to work well within a team environment
What is one business idea you’re willing to give away to our readers?
A secure and extremely easy to use wallet for digital assets
What is the best $100 you recently spent?
I randomly purchased a pack of baseball cards, and it reminded me of when I was a kid. Of course, I didn’t recognize most of the players…
Do you have a favorite book or podcast from which you’ve received much value?
My favorite podcast is Joe Rogan because of the extremely diverse set of guests he has on his show and his ability to foster interesting conversation with such a diverse group.
What’s a movie or series you recently enjoyed and why?
I recently re-watched Band of Brothers. I’m convinced it’s the greatest series ever made.
Key learnings:
- Be patient, both in your personal and professional life.
- Be persistent and open to change.
- Embrace change, and surrounding yourself with talented colleagues with a diverse skill set